The effects of monocyte/high-density lipoprotein ratio on hospital stay in patients with mild acute pancreatitis

Alper Sarı; Haydar Güngören; Elif Dizen Kazan; Semiha Orhan; Mustafa Duran; Sevnur Aysal Sarı; Erhan Bozkurt

doi:10.26900/hsq.1886

Authors

Alper Sarı Afyonkarahisar Health Sciences University / Türkiye 0000-0002-4327-8032
Haydar Güngören Afyonkarahisar Health Sciences University / Türkiye 0000-0002-6358-6630
Elif Dizen Kazan Afyonkarahisar Health Sciences University / Türkiye 0000-0003-3550-0964
Semiha Orhan Afyonkarahisar Health Sciences University / Türkiye 0000-0003-2617-6197
Mustafa Duran Afyonkarahisar Health Sciences University / Türkiye 0000-0001-9158-8214
Sevnur Aysal Sarı Afyonkarahisar State Hospital / Türkiye 0000-0002-6220-8742
Erhan Bozkurt Afyonkarahisar Health Sciences University / Türkiye 0000-0002-1853-7098

10.26900/hsq.1886

Abstract

In this study, we aimed to evaluate the effect of monocyte/high-density lipoprotein (MHR), which is associated with systemic inflammation: on prolonged hospitalization in patients with mild acute pancreatitis. Patients hospitalized for acute edematous pancreatitis between 01.01.2021 and 31.12.2021 were retrospectively screened. Arrival Ranson scores of the patients were calculated. Those with a Ranson score <3 were considered as mild acute pancreatitis and were included in the study. Patients with mild acute pancreatitis were divided into 2 groups with a hospital stay of <8 days and ≥8 days. Monocyte/HDL, biochemical and metabolic parameters were compared between the groups. The study was conducted with a total of 39 patients, 23 male (59%) and 16 female (41%). While 28 (71.8%) of the patients were discharged within <8 days, 11 (28.2%) were hospitalized for ≥8 days. Group ≥8 days was considered as prolonged hospitalization. It was determined that the monocyte/HDL ratio was significantly higher in the group with prolonged hospitalization between the groups. In univariate analyzes, it was determined that the presence of Diabetes Mellitus and MHR increased the risk of prolonged hospitalization by 5.25 times and 1.085 times, respectively. In the multivariate analysis of these two parameters, MHR was found to be an independent risk factor for prolonged hospitalization. It was concluded that monocyte/HDL can be used as a simple and reliable parameter to predict the duration of hospitalization in patients with mild acute pancreatitis.

Keywords:

Acute pancreatitis monocyte/high-density lipoprotein ratio prolonged hospital stay

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