The effects of monocyte/high-density lipoprotein ratio on hospital stay in patients with mild acute pancreatitis
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https://doi.org/10.26900/hsq.1886Keywords:
Acute pancreatitis, monocyte/high-density lipoprotein ratio, prolonged hospital stayAbstract
In this study, we aimed to evaluate the effect of monocyte/high-density lipoprotein (MHR), which is associated with systemic inflammation: on prolonged hospitalization in patients with mild acute pancreatitis. Patients hospitalized for acute edematous pancreatitis between 01.01.2021 and 31.12.2021 were retrospectively screened. Arrival Ranson scores of the patients were calculated. Those with a Ranson score <3 were considered as mild acute pancreatitis and were included in the study. Patients with mild acute pancreatitis were divided into 2 groups with a hospital stay of <8 days and ≥8 days. Monocyte/HDL, biochemical and metabolic parameters were compared between the groups. The study was conducted with a total of 39 patients, 23 male (59%) and 16 female (41%). While 28 (71.8%) of the patients were discharged within <8 days, 11 (28.2%) were hospitalized for ≥8 days. Group ≥8 days was considered as prolonged hospitalization. It was determined that the monocyte/HDL ratio was significantly higher in the group with prolonged hospitalization between the groups. In univariate analyzes, it was determined that the presence of Diabetes Mellitus and MHR increased the risk of prolonged hospitalization by 5.25 times and 1.085 times, respectively. In the multivariate analysis of these two parameters, MHR was found to be an independent risk factor for prolonged hospitalization. It was concluded that monocyte/HDL can be used as a simple and reliable parameter to predict the duration of hospitalization in patients with mild acute pancreatitis.
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Ignatavicius P, Gulla A, Cernauskis K, Barauskas G, Dambrauskas Z. How severe is moderately severe acute pancreatitis? Clinical validation of revised 2012 Atlanta Classification. World J Gastroenterol. 2017;23(43):7785–90. doi: 10.3748/wjg.v23.i43.7785.
Pitchumoni CS, Patel NM, Shah P. Factors influencing mortality in acute pancreatitis: Can we alter them? J Clin Gastroenterol. 2005;39(9):798-814. doi: 10.1097/01.mcg.0000177257.87939.00.
Sari A, Ulu Ms, Kazan S, Tunca O, Kazan Ed. Comparison of monocyte / HDL ratio in routine hemodialysis and peritoneal dialysis patients. Dicle Tıp Derg. 2020;47:139-7. doi: 10.5798/dicletip.706097.
PanWessex Study Group; Wessex Surgical Trainee Research Collaborative, Mirnezami A, Knight B, Moran B, Noble F, Branagan G, Primrose J, Pearson K, West M, Curtis N, Pucher P, Cuttress R, Pugh S, Underwood T. Population-based observational study of acute pancreatitis in southern England. Ann R Coll Surg Engl.2019;101(7):487-94. doi: 10.1308/rcsann.2019.0055.
Koçkan E, Doğan NÖ, Pekdemir M, Yılmaz S, Yaka E. Predictors of prolonged hospitalization in patients with mild and moderate pancreatitis presenting to the emergency department. Medizinische Klin - Intensivmed und Notfallmedizin. 2022;117(6):459-65. doi: 10.1007/s00063-021-00855-8.
Singh H, Gougol A, Mounzer R, Yadav D, Koutroumpakis E, Slivka A, et al. Which Patients with mild acute pancreatitis require prolonged hospitalization? Clin Transl Gastroenterol. 2017;8(12):E129. doi: 10.1038/ctg.2017.55.
Kaya Y, Düğeroğlu H, Çınar H. Akut pankreatitin şiddeti ile platelet lenfosit oranı arasındaki ilişki. FÜ Sağ Bil Tıp Derg. 2017;31(3):131-41.
Önmez A, Bilir E, Torun S. Akut pankreatit şiddeti ile trombosit lenfosit oranı, nötrofil lenfosit oranı, eritrosit dağılım genişliği ve ortalama platelet volümü arasındaki ilişki. Konuralp Tıp Derg. 2019;11(1):24-9. doi:10.18521/ktd.492274.
Han C, Zeng J, Lin R, Liu J, Qian W, Ding Z, et al. The utility of neutrophil to lymphocyte ratio and fluid sequestration as an early predictor of severe acute pancreatitis. Sci Rep. 2017;7(1):1-8. doi: 10.1038/s41598-017-10516-6.
Kanbay M, Solak Y, Unal HU, Kurt YG, Gok M, Cetinkaya H, et al. Monocyte count/HDL cholesterol ratio and cardiovascular events in patients with chronic kidney disease. Int Urol Nephrol. 2014;46(8):1619-25. doi: 10.1007/s11255-014-0730-1.
Ucar FM. A potential marker of bare metal stent restenosis: Monocyte count - to- HDL cholesterol ratio. BMC Cardiovasc Disord. 2016;16(1):1-7. doi: 10.1186/s12872-016-0367-3.
Peng YS, Chen YC, Tian YC, Yang CW, Lien JM, Fang JT, et al. Serum levels of apolipoprotein A-I and high-density lipoprotein can predict organ failure in acute pancreatitis. Crit Care. 2015;19(1):1-9. doi: 10.1186/s13054-015-0832-x
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