HEALTH SCIENCES QUARTERLY 2022-10-17T11:37:49+03:00 Buse AZLAĞ Open Journal Systems <p><strong>About the HSQ</strong></p> <p>Health Sciences Quarterly (E-ISSN: <a href="" target="_blank" rel="noopener">2791-6022</a>) journal as known by the name of "Journal of Scientific Perspectives" until April 2021 which has been published since 2017 is an international peer-reviewed journal of HOLISTENCE PUBLICATIONS. It is published quarterly in January, April, July, and October. All manuscripts submitted for publication are evaluated by the editor-in-chief, section editor, editorial board, and referees. In addition, the journal provides a medium for highlighting selected articles reporting highly significant original findings, as Editor's Choice Manuscripts.</p> First responders’ innovative methodology and curriculum definition for advanced virtual reality training 2022-08-08T10:19:41+03:00 Zeynep Sofuoğlu Turhan Sofuoğlu Débora Pérez Robles Federico Rodrigo Carjaval Eric Didderen Jóhanna Noraly Veeneklaas Aysel Başer <p>Within the ASSISTANCE Project (Adapted Situation Awareness Tools and Tailored Training Scenarios for Increasing the Capabilities and Enhancing the Protection of First Responders) the development of a novel and advanced training programme is currently underway to adapt to the needs and characteristics of first responders. Once the methodology was ready, a complete training curriculum was prepared in order to probe the concept of the European training network based on online Virtual Reality platforms. The curriculum is composed of subjects, which have been developed with a stepwise approach, taking into consideration the pre-requisites needed for<br />each subject and a gradual increase in difficulty and complexity. These subjects can be divided into two different types: theoretical subjects, which will be taught through the Moodle server and practical subjects, which will be taught through the performance of different virtual scenarios with the available Virtual Reality platforms. Each subject definition includes a short summary of the subject, their main, general and specific objectives as well as their preferred evaluation method and the pre-requisites needed. This paper presents the ASSISTANCE training methodology and the curriculum developed including the preliminary scheduling needed to complete all the proposed subjects.</p> 2022-10-17T00:00:00+03:00 Copyright (c) 2022 Holistence Publications Investigation of the protective effect of vitamin K1 on the heart in streptozotocin induced type 1 diabetes model 2022-06-08T19:16:26+03:00 Abdülkadir Bilir Esra Aslan <p>Maternal and fetal diabetes are directly associated with increased morbidity and mortality risk. Along with this increased risk, the incidence of congenital malformations in newborns also increases depending on the mother’s diabetes. Vitamin K1 is used as a therapeutic and protective agent in diabetes and various clinical conditions. For this reason, it was aimed to investigate the effect of vitamin K1 on chick embryo hearts immunohistochemically and morphologically by creating type 1 diabetes mellitus with streptozotocin in a chick embryo model. In our study, 5 different experimental groups will be created and a total of 50 SPF fertilized eggs, 10 in each group, will be used. The first group will be the control group, the second group will be the diabetes group, and the other three groups will be the treatment groups given different doses of vitamin K1. All solutions will be given on the 12th day of<br />incubation, and the hearts of all embryos will be analyzed immunohistochemically and morphologically on the 18th day of incubation. It was determined that the weight, length and ventricular thickness of the chick embryo hearts were statistically significantly decreased in the streptozotocin group compared to the control group embryo hearts. It was determined that the heart weights, lengths, and ventricular thicknesses increased depending on the dose of vitamin K1 compared to the streptozotocin group in the groups therapeutically administered vitamin K1 (p&lt;0.05). In addition, caspase-3 expression was also evaluated in our study, and a statistically significant increase was found in the streptozotocin group compared to the control group. Again, as a result of vitamin K1 administration, caspase-3 expressions decreased depending on the applied dose (p&lt;0.05). In conclusion, it was concluded that<br />the therapeutically applied vitamin K1 to diabetes mellitus reduces the degenerative and hyperplastic effects of diabetes mellitus.</p> 2022-10-17T00:00:00+03:00 Copyright (c) 2022 Holistence Publications Thoracic computed tomography measures have predictive value in the diagnosis of chronic obstructive pulmonary disease 2022-07-31T10:58:12+03:00 Mustafa Tosun Edhem Ünver Ali Küpeli Erdal Karavaş Sonay Aydın <p>Chronic Obstructive Pulmonary Disease (COPD) is diagnosed with pulmonary function tests (PFTs). However, since not all patients can be diagnosed with PFTs, some are diagnosed with radiological or clinical findings. The purpose of this study was to define the properties of obstructive airway disease through thoracic computed tomography (CT) and to identify the diagnostic efficacy of CT findings. A total of 160 patients who underwent PFT and thoracic CT assessment July 2018 - January 2019, were retrospectively analyzed. Based on PFT findings, patients were categorized into three groups as having normal, restrictive or obstructive airways. Age, height, weight, and body mass indexes of the groups were recorded. Pulmonary height, width, right-left hemi-diaphragm height, sterno-diaphragmatic angle and retrosternal transparent area length in axial sections were also recorded. Diagnostic efficacies of these parameters in the detection of obstructive airway disease were measured. Of the 160 patients (109 males, 51 females; mean age = 59.5), 91 (56.9) had normal PFT, 58 (36.2%) had obstructive and 11 (6.9%) had restrictive airway disease. Pulmonary height, width, sterno-diaphragmatic angle, and retrosternal transparent area length were significantly higher in patients with obstructive airway disease while the right-left hemi-diaphragm height was significantly lower (p&lt;0.001). About 60-75% sensitivity and specificity were obtained when identifying the obstructive airway disease with these parameters. These values obtained from the axial and sagittal sections could contribute to the diagnosis of obstructive airway disease.</p> 2022-10-17T00:00:00+03:00 Copyright (c) 2022 Holistence Publications The evaluation level of acute trauma pathologies by the emergency medicine physician assistant in abdominal computed tomography images of the trauma patients 2022-09-06T07:50:25+03:00 Mehmet Soyugüzel Ayşe Ertekin Esra Özgül <p>Abdominal injury is the third leading cause of death due to trauma. In this study, it is aimed to investigate the level of detection of acute trauma pathologies by the emergency medicine physician assistant in abdominal tomography images taken in trauma patients. Contrast-enhanced abdominal tomography images of 207 patients who applied with trauma between 12.15.2020 and 12.15.2021 were included in this study. In order to evaluate the images of the patients, the evaluation of the emergency medicine physician assistant was compared with the radiology official report. Patients’ age, gender, current complaints, symptoms, trauma classification, injury sites accompanying abdominal injury, hospitalization status and mortality rates were analyzed. The statistical distribution of the<br />patients’ demographic and clinical information was calculated. The reports of the patients whose radiology official report was issued and the emergency medicine assistant forms were transferred to the SPSS program as “pathology exists” or “no pathology”. In the study, 79.2% (n=164) were male and 20.8% (n=43) were female. The median age was 33 years. In terms of interpretation of abdominal tomography, a statistically significant correlation was found between the radiologist and the emergency medicine physician assistant in the evaluation of liver, spleen and kidney; intra-abdominal and retroperitoneal hemorrhage, muscle and fascia injury of abdominal wall; vertebral, iliac, ischiatic, pubic bone, sacrum and femoral neck fracture. It was determined that 12.1% (n=25) of the patients<br />were admitted to the intensive care unit and 5.3% (n=11) were died. High sensitivity, specificity, positive and negative predictive values were found in the evaluation of abdominal contrast-enhanced tomography imaging of patients admitted to the emergency department due to trauma by the emergency medicine assistant. We think that these high accuracy values are due to emergency medicine physician assistant’s evaluation of the patient’s history, physical examination and imaging studies as a whole.</p> 2022-10-17T00:00:00+03:00 Copyright (c) 2022 Holistence Publications An evaluation of patients who present to the emergency department with dizziness 2022-06-08T06:50:25+03:00 Oya Akpinar Oruç Nese Nur User <p>This study aimed to analyze the data of patients presenting with dizziness at our hospital’s emergency department (ED) by determining the etiology of dizziness and to contribute to the medical data of our country and the literature. This prospective study was conducted with 116 volunteering patients who presented to the Emergency Department of Afyon Kocatepe University, Faculty of Medicine for one year with dizziness complaints. After the anamnesis, physical examination, diagnostic tests (blood tests, Dix-Hallpike maneuver, audiological-vestibular tests, carotid-vertebral artery color Doppler ultrasonography, and computerized brain tomography), and psychiatric interrogation, the patients were divided into four etiology groups: Peripheral, central, psychogenic, and other causes of dizziness. Clinical features were compared between peripheral and central dizziness groups. A total of 116 (3.4%) of patient admissions to the emergency department complained of dizziness. Forty-nine (42.2%) of these patients were male, 67 (57.8%) were female. In the cohort, 33.9% were under 40, and dizziness increased with older age. Seventy (60.3%) patients had no formal education or were primary school graduates. The initial evaluation at the ED revealed that dizziness mostly shifted with the position (71.6%) and was mainly accompanied by headache (67.2%). Based on their diagnosis, 50 patients (43.1%) were in the peripheral group, 30 patients (25.8%) were in the central group, 22 patients (19%) were in the psychogenic dizziness group, and 14 patients (12%) were in the other causes group. Intergroup analysis between peripheral and central vertigo groups identified that the hearing loss, ear fullness, recent upper respiratory tract infection (URTI), nausea, vomiting, and shifting position was statistically significant (p&lt;0.05). Dizziness is one of the common complaints of admission to the ED and may arise from different etiologies. Our study demonstrated that psychogenic dizziness was common in this patient cohort.</p> 2022-10-17T00:00:00+03:00 Copyright (c) 2022 Holistence Publications Comparison of two different surgical techniques in the treatment of Fournier’s Gangrene 2022-09-26T15:39:40+03:00 Hasan Anıl Kurt Emre Onur Güven <p>Abstract<br />Fournier’s gangrene is a rapidly progressive, fatal, necrotizing fasciitis of the perineum and penoscrotal region which requires rapid intervention. This retrospective study compares the surgical outcomes of the fasciocutaneous flap and the embedding of the testicles into the thigh skin, applied for the reconstruction of penoscrotal defects after surgical debridement due to Fournier’s gangrene, in the light of the literature. A total of 110 patients treated for Fournier’s gangrene at Çanakkale Onsekiz Mart University, Faculty of Medicine, Department of Urology, Urology Clinic between 2009 and 2021 were evaluated retrospectively. Among these, 82 patients treated with fasciocutaneous flap and embedding of the testicles into the thigh skin for the reconstruction of penoscrotal defects were included in<br />the study. For these two wound closure methods, the cases were compared in age, hospital stay after debridement, hospital stay after wound closure, size of the debrided area, and postoperative complication parameters. There was no significant difference between the two groups in terms of age, comorbidity (hypertension, diabetes mellitus, etc.), and hospital stay after debridement. However, the length of hospital stay after wound closure and the size of the debrided area were significantly higher in patients with fasciocutaneous flap compared to the method in which the testis was embedded in the thigh. The fasciocutaneous flap application, which we apply for defects larger than 50% of the scrotum or extending beyond the scrotum, is a method that can be preferred by experienced surgeons for wound closure after Fournier gangrene debridement, considering patient comfort, since it does not create tension and blood supply to the testis is more comfortable. However, it would be more appropriate for the clinician to make a profit-loss calculation due to both the length of the operation and its more complex nature and the prolongation of the hospital stay after wound closure.</p> 2022-10-17T00:00:00+03:00 Copyright (c) 2022 Holistence Publications