Reproducibility of choroidal thickness measurements in hemodialysis patients: A spectral domain optical coherence tomography study
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Keywords

Hemodialysis
SD-OCT
Subfoveal Choroidal Thickness
Reproducibility

How to Cite

Uzel, M. M., Eroğul, Özgür, Eryiğit Eroğul, L., Taşlıpınar Uzel, A. G. ., İbiş, A., & Gobeka, H. H. (2022). Reproducibility of choroidal thickness measurements in hemodialysis patients: A spectral domain optical coherence tomography study. HEALTH SCIENCES QUARTERLY, 2(1), 39-44. https://doi.org/10.26900/hsq.2.1.05

Abstract

Aside from general body fluid fluctuation, hemodialysis (HD) may cause changes in ocular fluid balance, resulting in changes in subfoveal choroidal thickness (SFCT) and other ocular parameters. As a result, the purpose of this study was to investigate the effects of hemodialysis on the reproducibility of SFCT measured by spectral domain-optical coherence tomography (SD-OCT). Twenty-six HD (26 eyes) patients had their pre- and post-HD SFCT measured, and the results were compared for reproducibility. Following a thorough ophthalmic examination, SD-OCT was performed three times in a row during a single session. The same physician measured SFCT after automatically identifying choroid with a software caliper. Reproducibility parameters, including intra-class correlation coefficients (ICCs), coefficients of variation (COV), and test-retest variability (TRTV) were then calculated. Males made up 53.85% of the 26 HD patients. There was a significant IOP difference between pre-HD (16.42±3.14 mmHg) and post-HD (14.21±2.78 mmHg) (P<0.001). SFCT decreased significantly from pre-HD 243.50±10.23 μm to post-HD 234.29±9.41 μm (P<0.001). ICC value increased significantly after HD, rising from 0.948 to 0.989 (P<0.001, for all). Pre- and post-HD COV values were 1.6% and 0.65%, respectively. Also, pre- and post-HD TRTV values were 7.864±1.996 μm and 3.074±1.536 μm, respectively. In this study, the reproducibility of SFCT as measured by OCT was lower during pre-HD compared to post-HD. Post-HD SD-OCT assessment appears to improve the reliability of clinical outcomes in the diagnosis and monitoring of HD patients.

https://doi.org/10.26900/hsq.2.1.05
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