THE IMPORTANCE OF THE MEDICINAL PLANT NASTURTIUM OFFICINALE L. IN THE ANTICANCER ACTIVITY RESEARCH
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https://doi.org/10.26900/jsp.3.016Keywords:
antiviral, antiinflammatory,diuretic, expectorant, anti-diabetic, hepatoprotective, antihyperlipidemic and anticancerAbstract
Cancer is known as one of the main cause of deathworldwide. It is difficult to discover nove lagents that selectively kill tumor cels or inhibit their proliferation without general toxicity. Searching for more active, more selective and less toxic compounds are the main targets of cancer researchs. Nasturtium officinale L. has been used for a long time as a food and medicinal plant widely distrubuted areas of world for ages.Main therapeutic effect of plant is because of rich essential nutrients as well as non-essential health-promoting phytochemicals phenolics and glucosinolates. The plant has antiviral, antiinflammatory,diuretic, expectorant, anti-diabetic, hepatoprotective, antihyperlipidemic and anticancer properties. The aim of this study is to review the Nasturtium officinale L. compounds and search for their effects against various cancer cell lines.
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References
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[25] ROSE, P., HUANG, Q., ONG, C.N., WHITEMAN, M., 2005, Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol. 209 (2), 105-113.
[26] SYED ALWI, S. S., CAVELL, B. E., TELANG, U., MORRIS, M. E., PARRY, B. M., PACKHAM, G., 2010, In vivo modulation of 4E binding protein 1 (4E-BP1) phosphorylation by watercress: a pilot study. The British journal of nutrition, 104 (9), 1288-96.
[27] CAVELL, B.E., SYED ALWI S.S., DONLEVY, A., PACKHAM, G., 2011, Antiangiogenic effects of dietary isothiocyanates: mechanisms of action and implications for human health, Biochem Pharmacol. 81 (3), 327-36.
[28] PAN, J H., ABERNATHY, B., KIM, Y. J., LEE J. H., KIM, J. H., SHIN, E. C., KIM J. K., 2018, Cruciferous vegetables and colorectal cancer prevention through microRNA regulation: A review, Critical Reviews in Food Science and Nutrition, 58 (12), 2026-2038.
[2] BARKER, D.J., 2009, Pacific Northwest Aquatic Invasive Species Profile: Nasturtium officinale (Watercress).
https://depts.washington.edu/oldenlab/wordpress/wpcontent/uploads/2013/03/Nasturtium-officinale_Barker.pdf
[3] DOLATKHAHI, M., DOLATKHAHI, A., & NEJAD, J.B., 2014, Ethnobotanical study of medicinal plants used in Arjan- Parishan protected area in Fars Province of Iran. Avicenna journal of phytomedicine, 4(6), 402-12.
[4] ANDRADE, J. M., LUCERO MOSQUERA, H., & ARMIJOS, C., 2017. Ethnobotany of Indigenous Saraguros: Medicinal Plants Used by Community Healers"Hampiyachakkuna" in the San Lucas Parish, Southern Ecuador. BioMed research international, 9343724.
[5] ABBASI, A.M., KHAN, M.A., SHAH, M.H., SHAH, M.M., PERVEZ, A., AHMAD, M., 2013, Ethnobotanical appraisal and cultural values of medicinally important wild edible vegetables of Lesser Himalayas-Pakistan, J. Ethnobiol. Ethnomed., 9(1), 66.
[6] S. AL-QURA`N. ,2006. Ethnobotany of Folk Medicinal Potentiality of Aquatic Plants in Jordan. Research Journal of Botany, 1, 75-84.
[7] FLAVIA, L. P., JOSE, M. F., JOAO, P. V. L., 2012. Ethnopharmacological survey: a selection strategy to identify medicinal plants for a local phytotherapy program. Brazilian Journal of Pharmaceutical Sciences, 48, (2).299-313.
[8] FAWZI MAHOMOODALLY, M., PRIYAMKA SREEKEESOON D., 2017, A Quantitative Ethnopharmacological Documentation of Natural Pharmacological Agents Used by Pediatric Patients in Mauritius, BioMed Research International, 1-14.
[9] AIRES, A., CARVALHO, R., ROSA, E.A.S., SAAVEDRA M. J., 2013, Phytochemical characterization and antioxidant properties of baby-leaf watercress produced under organic production system, CyTA , Journal of Food, 11:4, 343-351.
[10] ZEB, A., 2015, Phenolic profile and antioxidant potential of wild watercress (Nasturtium officinale L.). SpringerPlus, 4, 714.
[11] HARO, G., IKSEN, I., RUMANTİ, R.M., MARBUN, N., SARİ, R.P., GULTON, R.P.J., 2018, Evoluation of Antioxidant activity and Minerals Value From Watercress (Nasturtium officinale R.Br.), 11 (1), 232-237.
[12] PAHWA, R., JIALAL, I., 2018, Chronic Inflammation. StatPearls Publishing LLC, Treasure Island (FL).
[13] BALISTRERI, C.R., CARUSO, C., CANDORE, G., 2010, The role of adipose tissue and adipokines in obesity-related inflammatory diseases. Mediat Inflamm, 802078.
[14] LIBRA, M., NICOLETTI, F., 2017, Diet, inflammation and cancer: a journey from prevention to treatment. In: Accardi G, Caruso C, editors. Updates in pathobiology: causality and chance in ageing, age-related diseases and longevity. Palermo, University Press, 145–162.
[15] ACCARDI, G., CARUSO, C., 2018, Immune-inflammatory responses in the elderly: an update. Immun Ageing, 15, 1-11.
[16] SANTOS J, OLIVEIRA MBPP, IBÁÑEZ E, HERRERO M. 2014, Phenolic profile evolution of different ready-to-eat baby-leaf vegetables during storage. J Chromatogr A.1327:118–31.
[17] AIRES, A., CARVALHO, R., ROSA, EAS, SAAVEDRA, M.J. 2013, Phytochemical characterization and antioxidant properties of baby-leaf watercress produced under organic production system. CyTA - J Food., 11, 343–51.
[18] MARTÍNEZ-SÁNCHEZ, A., GIL-IZQUIERDO, A., GIL, M.I., FERRERES F., 2008, A comparative study of flavonoid compounds, vitamin C, and antioxidant properties of baby leaf Brassicaceae species. J Agric Food Chem., 56, 2330–2340.
[19] DI NOIA, J., 2014, Defining powerhouse fruits and vegetables: a nutrient density approach. Preventing chronic disease, 11, 1-5.
[20] HEBATOLLAH, S., MOSTAFAZADEH, M., SADEGHI, H., MNADERİAN, MEHRZAD JAFARİ BARMAK, MOHAMMAD SHARİF TALEBİANPOOR & FOUAD MEHRABAN (2014) In vivo anti-inflammatory properties of aerial parts of Nasturtium officinale, Pharmaceutical Biology, 52(2), 169-174.
[21] SHAHANI, S., BEHZADFAR, F., JAHANI, D., GHASEMI, M., SHAKI, F., 2017, Antioxidant and anti-inflammatory effects of Nasturtium officinale involved in attenuation of gentamicin-induced nephrotoxicity, Toxicology Mechanisms and Methods, 27(2), 107-114.
[22] GILL, C.I., HALDAR, S., BOYD, L.A., BENNETT, R., WHITEFORD, J., BUTLER, M., PEARSON, J.R., BRADBURY, I., ROWLAND, I.R., 2007. Watercress supplementation in diet reduces lymphocyte DNA damage and alters blood antioxidant status in healthy adults. Am J Clin Nutr. 85, 504–510.
[23] LAI K.C., HSU, S.C., KUO, C.L., IP, S.W., YANG, J.S., HSU, Y.M., HUANG H.Y., WU S.H., CHUNG, J.G., 2010, Phenethyl Isothiocyanate Inhibited Tumor Migration and Invasion via Suppressing Multiple Signal Transduction Pathways in Human Colon Cancer HT29 Cells, Journal of Agricultural and Food Chemistry, 58 (20), 11148-11155.
[24] PEREIRA LUCÍLIA, P., SILVA P., DUARTE, M., RODRIGUES, L., DUARTE C. M. M, ALBUQUERQUE, C., TERESA SERRA, A., 2017, Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study, Nutrients, 9(4), 368.
[25] ROSE, P., HUANG, Q., ONG, C.N., WHITEMAN, M., 2005, Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol. 209 (2), 105-113.
[26] SYED ALWI, S. S., CAVELL, B. E., TELANG, U., MORRIS, M. E., PARRY, B. M., PACKHAM, G., 2010, In vivo modulation of 4E binding protein 1 (4E-BP1) phosphorylation by watercress: a pilot study. The British journal of nutrition, 104 (9), 1288-96.
[27] CAVELL, B.E., SYED ALWI S.S., DONLEVY, A., PACKHAM, G., 2011, Antiangiogenic effects of dietary isothiocyanates: mechanisms of action and implications for human health, Biochem Pharmacol. 81 (3), 327-36.
[28] PAN, J H., ABERNATHY, B., KIM, Y. J., LEE J. H., KIM, J. H., SHIN, E. C., KIM J. K., 2018, Cruciferous vegetables and colorectal cancer prevention through microRNA regulation: A review, Critical Reviews in Food Science and Nutrition, 58 (12), 2026-2038.
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Published
2019-04-30
How to Cite
YALÇINKAYA, E., ÖZGÜÇ, S., TÖRER, Y. O., & ZEYBEK, U. (2019). THE IMPORTANCE OF THE MEDICINAL PLANT NASTURTIUM OFFICINALE L. IN THE ANTICANCER ACTIVITY RESEARCH. HEALTH SCIENCES QUARTERLY, 3(2), 159–164. https://doi.org/10.26900/jsp.3.016
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