Trends in awareness of rational drug use in healthcare: A scientific perspective
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https://doi.org/10.26809/joa.2936Keywords:
Health, Rational Drug Use, Awareness, Trend, Bibliometric AnalysisAbstract
This study aims to reveal the research trends in the field of rational drug use in healthcare published in the Web of Science database, the most frequently studied topics, the concepts and keywords used, the most frequently published and cited authors, journals, universities, countries and their scientific collaboration networks. A total of 438 research articles were included in the study based on the identified keywords. Analyses were conducted in the R programming language (using the bibliometrix package and Biblioshiny via RStudio). The findings indicate that research on rational drug use gained momentum, particularly after 2009, with citations peaking in 2016. Countries such as Brazil, China, and India, journals such as Revista de Saude Publica, BMC Health Services Research, Frontiers in Pharmacology, and the Federal University of Rio Grande do Sul and the Federal University of Minas Gerais are leading the way in production, while Türkiye has made limited contributions to the field. Thematic analysis revealed that concepts such as care, health, medicines, resistance, and management were prominent. Keyword trends reveal increased interest in concepts such as drug use indicators, antimicrobial resistance, rational use, information, and education. Overall, this study holistically analyzed the intellectual structure, thematic orientations, and research gaps of the literature on rational drug use and offered strategic directions for future research.
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AKARSU, T. and AKGÜLLÜ, Ç. (2024). The effect of rational drug usage on disease adaptation and quality of life in geriatric patients with cardiac insufficiency. Avrasya Sağlık Bilimleri Dergisi, 7(2), 98–105. https://doi.org/10.53493/avrasyasbd.1435125
ARIA, M. and CUCCURULLO, C. (2017). Bibliometrix: An R-tool for comprehensive science mapping analysis. Journal of Informetrics, 11(4), 959–975. https://doi.org/10.1016/j.joi.2017.08.007
BARROS, R. D. D., COSTA, E. A., SANTOS, D. B. D., SOUZA, G. S., ÁLVARES, J., GUERRA JUNIOR, A. A., ... & LEITE, S. N. (2017). Access to medicines: relations with the institutionalization of pharmaceutical services. Revista de Saude Publica, 51, 8s. https://doi.org/10.11606/S1518-8787.2017051007138
BUDIONO, J., RIFAI, A., SAPUTRA, A. and HANDAYANI, S. (2024). A bibliometric analysis of geotextile as underground filtration in subsurface drainage towards slope stability using VOSviewer. Journal of World Science, 3(6), 648–659. https://doi.org/10.58344/jws.v3i6.630
COSTA, C. M. F. N., SILVEIRA, M. R., ACURCIO, F. D. A., GUERRA, A. A., GUIBU, I. A., COSTA, K. S., ... & ÁLVARES, J. (2017). Use of medicines by patients of the primary health care of the Brazilian Unified Health System. Revista de Saúde Pública, 51(suppl 2), 18s. https://doi.org/10.11606/S1518-8787.2017051007144
ÇAKMAK, V. S. and PAKYÜZ, S. Ç. (2020). Metodolojik bir çalışma: Akılcı İlaç Kullanımı Ölçeği’nin geliştirilmesi. Journal of Anatolia Nursing and Health Sciences, 498–507. https://doi.org/10.17049/ataunihem.595394f
DIODATO, V. P. and GELLATLY, P. (2013). Dictionary of Bibliometrics. Routledge.
DIRIK, D., ERHAN, T. and ERYILMAZ, İ. (2024). Yapay zekâ ve örgüt temelli araştırmaların potansiyel eğilimleri üzerine bibliyometrik bir analiz. Bulletin of Economic Theory and Analysis, 9(3), 669–698. https://doi.org/10.25229/beta.1487924
EKİCİ, Ö. (2023). Evaluation of knowledge and attitudes regarding rational drug use of individuals applying to the oral and maxillofacial surgery clinic: a cross-sectional study. Turkiye Klinikleri Journal of Dental Sciences, 29(2), 216–224. https://doi.org/10.5336/dentalsci.2022-93234
FLEXA, R. G., SOUZA, J. G., ÁLVARES, J., et al. (2021). Clinical pharmacy in Brazil: A bibliometric analysis. International Journal of Development Research, 11(4). https://doi.org/10.37118/ijdr.21512.04.2021
GIANNETTA, N., DIONISI, S., TONELLO, M., SIMONE, E. D. and MUZIO, M. D. (2022). A worldwide bibliometric analysis of published literature on medication errors. Journal of Patient Safety, 18(3), 201–209. https://doi.org/10.1097/pts.0000000000000894
KOKOL, P., VOŠNER, H. and ZAVRŠNIK, J. (2020). Application of bibliometrics in medicine: A historical bibliometrics analysis. Health Information and Libraries Journal, 38(2), 125–138. https://doi.org/10.1111/hir.12295
MEKONNEN, B. D., AYALEW, M. Z. and TEGEGN, A. A. (2021). Rational drug use evaluation based on World Health Organization core drug use indicators in Ethiopia: A systematic review. Drug, Healthcare and Patient Safety, 13, 159–170. https://doi.org/10.2147/dhps.s311926
MOUSAVI, S., MANSOURI, A. and AHMADVAND, A. (2013). A bibliometric study of publication patterns in rational use of medicines in Iran. Pharmacy Practice, 11(1), 38. https://doi.org/10.4321/s1886-36552013000100007
OLIVEIRA, D. F., LIMA, R. A. and SOUZA, C. L. (2022). Rational drug use in public health systems: A Brazilian perspective. BMC Health Services Research, 22(1), 334. https://doi.org/10.1186/s12913-022-07705-w
ÖZDAMAR, İ. and ÖZDAMAR, E. N. (2021). Drug utilization pattern and rational drug use at orthopedics and traumatology outpatient clinics: A cross-sectional study. Joint Diseases and Related Surgery, 32(3), 759–766. https://doi.org/10.52312/jdrs.2021.211
PASSAS, I. (2024). Bibliometric analysis: The main steps. Encyclopedia, 4(2), 1014–1025. https://doi.org/10.3390/encyclopedia4020065
RAYA, M. T., HASSAN, Z. and NOOR, S. M. (2023). Digital health literacy and rational medicine use: A cross-sectional study among university students. International Journal of Medical Informatics, 174, 105044. https://doi.org/10.1016/j.ijmedinf.2023.105044
SHI, H., TAN, X., SHU, J., ZHOU, J., DAN, S., YANG, L., … & CHEN, Z. (2024). Knowledge, attitude, and practice of medication and its influencing factors among residents in western China: A large-scale cross-sectional study. Frontiers in Medicine, 11. https://doi.org/10.3389/fmed.2024.1303672
SHRESTHA, S., DANEKHU, K., KC, B., PALAIAN, S. and IBRAHIM, M. I. M. (2020). Bibliometric analysis of adverse drug reactions and pharmacovigilance research activities in Nepal. Therapeutic Advances in Drug Safety, 11. https://doi.org/10.1177/2042098620922480
SRIVASTAVA, R. and SRIVASTAVA, S. (2022). Bibliometric analysis of Indian Journal of Palliative Care from 1995 to 2022 using the VOSviewer and Bibliometrix software. Indian Journal of Palliative Care, 28, 338–353. https://doi.org/10.25259/ijpc_30_2022
STORENG, K. and PUYVALLÉE, A. (2018). Civil society participation in global public private partnerships for health. Health Policy and Planning, 33(8), 928–936. https://doi.org/10.1093/heapol/czy070
TANG, Q., WAN, L., LU, J., WU, W., WU, H., LIU, Z., … & LÜ, J. (2022). Rational medication management mode and its implementation effect for the elderly with multimorbidity: A prospective cohort study in China. Frontiers in Public Health, 10. https://doi.org/10.3389/fpubh.2022.992959
WORLD HEALTH ORGANIZATION. (2015). Global action plan on antimicrobial resistance. Geneva: WHO.
YANG, J., ZHENG, L., GUAN, Y. and SONG, C. (2019). Analysis of the impact of antimicrobial management and rational use of antibiotics. European Journal of Hospital Pharmacy, 27(5), 286–291. https://doi.org/10.1136/ejhpharm-2018-001609
YAO, R., SHEN, Z., XU, X., LING, G., XIANG, R., SONG, T., … & ZHAI, Y. (2024). Knowledge mapping of graph neural networks for drug discovery: A bibliometric and visualized analysis. Frontiers in Pharmacology, 15. https://doi.org/10.3389/fphar.2024.1393415
YILMAZ, C. K. and KIL, A. (2018). Individuals' health literacy level and their knowledge and practices with respect to rational drug use. Kontakt, 20(4), e401–e407. https://doi.org/10.1016/j.kontakt.2018.08.001
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